Clinical impact of the metabolic phenotype of prostate cancer: role of monocarboxylate transporters (MCTs)
نویسندگان
چکیده
Materials and methods Expression of key metabolic markers was assessed by immunohistochemistry in 480 prostate samples and prostate cell lines. The levels of glycolytic metabolism were assessed using commercial colorimetric assays. The effect of the MCT inhibitor and thioridazine was evaluated on cell viability by using the Sulforhodamine B assay. Finally, ultra-structural studies were performed by classical electron microscopy transmission techniques.
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